Healthcare is facing an uncertain future. People are living longer, costs are rising and patients are demanding a different experience. Over the past 15 years, a growing number of health systems have built in-house innovation labs to survive (and thrive) in this emerging world. Often enabled by design, it was the emergence of these labs that prompted interest in examining them further. Using a qualitative approach including expert interviews, this research explored 17 hospital based design labs around the world. It is hoped that this research may be used by others seeking to advance health design in their own organizations and to provoke discussion and thought on the use of design in the context of healthcare innovation. Outputs of this research include a Synthesis Map of the findings and a Health Design Lab Canvas. The Health Design Lab Canvas is accompanied by design principles for consideration when building a health design lab in a healthcare organization.