Googling DNA sequences on the World Wide Web
Hajibabaei, Mehrdad and Singer, Gregory AC (2009) Googling DNA sequences on the World Wide Web. BMC Bioinformatics, 10 (Suppl). S4. ISSN 1471-2105
Available under License Creative Commons Attribution.
Download (207kB) | Preview
Background: New web-based technologies provide an excellent opportunity for sharing and
accessing information and using web as a platform for interaction and collaboration. Although
several specialized tools are available for analyzing DNA sequence information, conventional webbased
tools have not been utilized for bioinformatics applications. We have developed a novel
algorithm and implemented it for searching species-specific genomic sequences, DNA barcodes, by
using popular web-based methods such as Google.
Results: We developed an alignment independent character based algorithm based on dividing a
sequence library (DNA barcodes) and query sequence to words. The actual search is conducted by
conventional search tools such as freely available Google Desktop Search. We implemented our
algorithm in two exemplar packages. We developed pre and post-processing software to provide
customized input and output services, respectively. Our analysis of all publicly available DNA
barcode sequences shows a high accuracy as well as rapid results.
Conclusion: Our method makes use of conventional web-based technologies for specialized
genetic data. It provides a robust and efficient solution for sequence search on the web. The
integration of our search method for large-scale sequence libraries such as DNA barcodes provides
an excellent web-based tool for accessing this information and linking it to other available
categories of information on the web.
|Divisions:||Faculty of Art|
|Date Deposited:||03 Nov 2016 16:39|
|Last Modified:||05 Feb 2017 06:52|
Actions (login required)