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Genome-wide analysis of core promoter elements from conserved human and mouse orthologous pairs

Jin, Victor X. and Singer, Gregory AC and Agosto-Pérez, Francisco J. and Liyanarachchi, Sandya and Davuluri, Ramana V. (2006) Genome-wide analysis of core promoter elements from conserved human and mouse orthologous pairs. BMC Bioinformatics, 7. p. 114. ISSN 1471-2105

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Official URL: http://dx.doi.org/10.1186/1471-2105-7-114

Abstract

The canonical core promoter elements consist of the TATA box, initiator (Inr), downstream core promoter element (DPE), TFIIB recognition element (BRE) and the newly-discovered motif 10 element (MTE). The motifs for these core promoter elements are highly degenerate, which tends to lead to a high false discovery rate when attempting to detect them in promoter sequences.

Item Type: Article
Date Deposited: 21 Oct 2016 14:37
Last Modified: 05 Feb 2017 15:59
URI: http://openresearch.ocadu.ca/id/eprint/1255

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